So PRRT is a molecular technique in which a radioisotope which is labeled with a small body which actually targets a particular receptor which is known as the somatostatin receptors is used to treat a specific kind of tumor known as a Neuroendocrine Tumor.
Now Neuroendocrine Tumors are malignant tumors which can arise from any part of the body most commonly either they arise from the pancreas or any part of the small or large bowels or can arise from the lungs or in certain cases it can even arise from the adrenal glands in which case they are known as Pheochromocytomas or they may arise along the sympathetic chain and be called paragangliomas.
Now these tumors when they metastasized they become… they can cause a lot of problems in the patient initially things like flushing, weight loss, diarrhea, raised insulin levels leading to hypoglycemia or it depends on if they are… these Neuroendocrine Tumor cells they secrete certain hormones which cause these changes in the body so it depends on the kind of neuro transmitter or hormone which this particular Neuroendocrine Tumors secretes and the patient may have symptoms depending on the kind of Neuroendocrine Tumor which he has. Most patients will may present with just diarrhea, or increased acidity or sometimes ulcers in the abdomen may present with interstellar obstruction. Now these Neuroendocrine Tumors specially the well differentiated Neuroendocrine Tumors are often refectory to chemotherapy.
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